Synonyms for Antagonize:

n.

madden, drive someone mad, frustrate, provoke. antagonize (noun)
antagonise, counteract.

v.

aggravate (verb)
discompose, hassle, needle, fret, envenom, harass, rankle, arouse, bait, bother, aggravate, chafe, exasperate, enrage, trouble, badger, inflame, bedevil, irritate, irk, grate, infuriate, tease, peeve, harry, pester, disturb, annoy, vex, upset, nag, perturb, torment, exacerbate.
alienate (verb)
anger, set against, alienate, offend.
cause problem; oppose (verb)
annoy, irritate, anger, alienate, struggle, counteract, offend, repel.
conflict (verb)
brawl, blast, dissent, collide, squabble, differ, contend, disagree, conflict, spar, clash, clamor, altercate, riot, row, bicker, broil, feud.
contend (verb)
defend, face, quarrel, encounter, stand, confront, wrangle, vie, contrast, struggle, oppose, withstand, protest, wrestle, resist, argue, dispute.
disagree (verb)
reject, challenge, demur, complain, object, defy, repudiate.
emotion (verb)
antagonise.
oppose (verb)
counter, impede, repulse, meddle, contradict, intercept, fight, interfere, counteract, suppress, check, repel, counterattack, repress, inhibit, hinder, oppress, rebuff, cross, obstruct.

Other synonyms:

madden. anger, provoke, frustrate. estrange
alienate.
poison
envenom.
Other relevant words:
antagonise, madden, anger, alienate, set against, frustrate, offend, provoke.

Usage examples for antagonize

  1. Was it wise to antagonize them? – The Puppet Crown by Harold MacGrath
  2. And the last thing I wish to do here is to antagonize the rougher element. – The Heart of Canyon Pass by Thomas K. Holmes