Mule skinner is a colloquial term used to describe individuals who work with mules for transportation purposes. However, there are a variety of synonyms that can be used to describe a mule skinner. Some potential alternatives include packers, teamsters, muleteers, or even simply mule drivers. Each of these terms captures a slightly different aspect of the job, but all describe someone who works with mules in some capacity. Whether you're looking for a more technical term or just want to add some variety to your vocabulary, there are plenty of alternatives to mule skinner that can be used to describe this unique occupation.