Synonyms for Loco:

adj.

insane (adjective)
dotty, moonstruck, loony, daft, nutty as a fruitcake, screwy, sick in the head, of unsound mind, brainsick, crackers, crazy as a loon, fruity, touched, mentally ill, disordered, bananas, cracked, distraught, not all there, demented, unsound, maniac, maniacal, lunatic, cuckoo, batty, off, unbalanced, around the bend, mad, nutty, mad as a hatter, nuts, stark raving mad.
lunatic (adjective)
kooky.

n.

loco (noun)
buggy, cracked, dotty, bonkers, balmy, kooky, barmy, around the bend, nutty, loony, wacky, nuts, batty, round the bend, loopy, haywire, crackers, whacky, fruity, insane, kookie, bats, daft.

Other synonyms:

mentally ill, brainsick, bananas, Daffy. demented, maniacal, unbalanced, screwy, lunatic, non compos mentis, distraught. moonstruck, disordered, unsound, touched. mad. off.

Usage examples for loco

  1. 30, 'Crispum equestri ortum loco C. Sallustius, rerum Romanarum florentissimus auctor, sororis nepotem in nomen adscivit. – The Student's Companion to Latin Authors by George Middleton Thomas R. Mills
  2. " You'll go loco give you time," scoffed Levins. – 'Firebrand' Trevison by Charles Alden Seltzer
  3. Or are you just simple loco – Smoke Bellew by Jack London