Synonyms for Destruction:

n.

extinction, falling, formation, slaughter, assassination, despoliation, subversion, bombardment, crashing, overthrow, sack, harm, disruption, depredation, butchery, ruin, vandalism, liquidation, sabotage, carnage, wreck, the ravages of something, consumption, burning, production, wrecking, collision. leftover, ruination, wrack, help. breakage. wrecker, destroyer. act (noun)
devastation.
annulment (noun)
cancellation, nullification, abolition, withdrawal, elimination, revocation, Disclamation, invalidation, abolishment, dissolution, negation, refutation, dismissal, neutralization, eradication, repudiation, divorce, Disaffirmation, disavowal, retraction, undoing, abnegation, rejection, deletion, obliteration, annulment, Extinguishment, denial.
breakage (noun)
impairment.
damage (noun)
sabotage.
demolition, devastation (noun)
extinction, annihilation, wreckage, abolition, elimination, loss, eradication, invalidation, liquidation, overthrow, havoc, wrecking, carnage, extermination, downfall, bane, extirpation, subversion, undoing, crashing, ruination, slaughter, end, ruin.
destruction (noun)
disintegration, death, desolation, decimation, wreckage, annihilation, downfall, vaporization, end, extermination, holocaust, devastation, extirpation, demolition, havoc.
havoc (noun)
havoc.
killing (noun)
slaughter.
ruin (noun)
ruin, ruination, subversion, dilapidation.
ruination (noun)
wrecker.
ruins (noun)
Ashes.
state (noun)
end, death.
waste (noun)
waste.

Other synonyms:

loss, formation, impairment, ruination, wrack, ruin, bane, consumption, wrecker, wreck. harm, breakage. destroyer. decay. annihilation
extinction.
demolition
sabotage, demolition.
injury
damage.
pillage
depredation.
piracy
vandalism.
plunder
despoliation.
slaughter
carnage.
submission
prostration.

Usage examples for destruction

  1. The destruction of property by this flood was immense. – The History of Louisville, from the Earliest Settlement till the Year 1852 by Ben Casseday
  2. That's what he was, a- teasin' an' misleadin' a poor old man into destruction – Dorothy at Oak Knowe by Evelyn Raymond