Profligates are individuals who are reckless and wasteful in their behavior and spending. There are a variety of synonyms that can be used to describe such individuals. Some of the most common ones include spendthrifts, prodigals, squanderers, wasters, and hedonists. Each of these words carries a slightly different connotation, but they all refer to individuals who have a tendency to use up resources in a careless or extravagant way. Other less common synonyms for profligates include dissolute, extravagant, and debauched. Whether you are discussing someone's spending habits or their overall lifestyle, using one of these synonyms can help you communicate more effectively and convey the appropriate tone and meaning.