Synonyms for Out-and-out:

adj.

absolute (adjective)
unmitigated, crashing.
all (adjective)
downright, absolute, sheer, right-down, rank.
all-encompassing (adjective)
thorough.
complete (adjective)
total, absolute, thoroughgoing, unqualified, utter, outright, arrant, consummate, downright, unmitigated, perfect, thorough.
dead (adjective)
entire.
flagrant (adjective)
arrant.
perfect (adjective)
perfect.
positive (adjective)
positive.

n.

babyish, constitutionally, flexible, born, adaptive, classy, Clingy, addictive, flawed, badass. out-and-out (noun)
downright, rank, sheer, right-down, absolute, complete.

v.

complete (verb)
thorough.

Other synonyms:

crashing, unrelieved, arrant. thoroughgoing. flat out, pure, unlimited, unbounded, all-out, consummate. blooming, unequivocal. damned, unqualified. positive, unreserved. dead, perfect, complete. flat. downright
downright, outright.