Synonyms for Open up:

n.

help along, carry, allow, let, lubricate, permit, encourage, qualify, put through. attend, bandage, cauterize, bleed, bypass, anesthetize, catch, anaesthetize, bring back, catheterize. work, curl, bend, form, reshape, shape, deform, twist, straighten. decentralise, decentralize, deindustrialize, democratise, denationalize, centralize, develop, centralise, democratize, devolve. drive a wedge between, play both ends (against the middle), come between, set against, divide, ignite, tear apart, strain. burst open, crack something open, unlock, unscrew, force, pry, undo, try. open up (noun)
open, pioneer.

v.

acknowledge (verb)
allow.
admit (verb)
let, permit, talk.
change (verb)
open.
divulge (verb)
give away.
originate (verb)
form.
pioneer (verb)
begin.
reveal (verb)
begin, grow, start.

Other synonyms:

straighten, unscrew, permit, qualify, begin, deform, let, encourage. come between, allow, twist, reshape, pry, bend, curl, set against, fire off, lubricate, put through. ignite, shape. tear apart, let off. carry. fire, form. load, try, work. discharge. divide. strain. fight. force.