Synonyms for Of course:

adv

without doubt (adverb)
certainly.

adv.

as expected (adverb)
naturally, by all means, definitely, certainly.
certainly (adverb)
sure.
indeed (adverb)
naturally.

n.

absolutely, exactly, right, O.K., precisely, great, agreed. cool, I know, I see/take your point, if you like, I see, I know what you mean, GOTCHA. definitely, that's right, by all means, you're on, sure, I don't mind if I do, uh-huh, yes. all-right, as you wish, if you (really) must, if you want, I don't see why not, help yourself, certainly. sure-enough, that's not saying much, anyway, what do/can you expect?, typical, it/that figures, I thought as much, as you might expect/imagine. of course (noun)
course, naturally.

Other synonyms:

uh-huh, agreed, precisely, exactly. absolutely, cool, O.K., GOTCHA, typical, definitely, certainly. great. anyway, right. all-right. surely
yes.
Other relevant words:
certainly, yes, definitely, exactly, by all means, right, absolutely, uh-huh, precisely, sure.