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doltish, jackass, crackpot, moronic, dotty, meat-headed, dumb, bone-headed, asinine, ignorant, idiotic, half-witted, stupid, absurd, brainless, blithering, blockheaded, goofy, foolish, imbecilic, nitwit, chuckle-headed, dopey, cretinous, dim-witted, lame-brained, inane, nonsensical, crazy, knuckle-headed.
zesty, maniacal, bubbleheaded, wacky, lunkheaded, batty, weak-minded, gaga, fruity, eccentric, unwise, madman, weirdie, ding-a-ling, mental, crazed, disordered, mentally ill, psycho, dotty, maniac, haywire, scatty, touched, cockamamie, barmy, loony tunes, bedlam, bonkers, bughouse, unearthly, loco, headcase, looney, dingbat, unhinged, lunatic, space cadet, kooky, inept, fatuous, kookie, childish, not in your right mind/not right in the head, senseless, cockeyed, wise, ability, kook, daft, featherheaded, deranged, oddity, sappy, meshuga, loon, certifiable, mad, screwball, non compos mentis, cracked, zany, bats, simpleminded, tomfool, ridiculous, crank, crackers, dippy, creep, distraught, mild, sane, yeasty, madwoman, wud, laughable, wild, nutty, chapped, preposterous, whacky, buggy, bananas, cuckoo, demented, half-baked, cranky, nutlike, nut, insane, nutjob, wacko, jerky, soft, oddball, silly, amiss, awry, crazy, witless, roughened, nuts, psychotic, daffy, around the bend, zestful, weirdo, nutcase, off, alligatored, round the bend, screwy, unbalanced, harebrained, brainsick, wrong, cockamamy, over-the-top, weirdy, loopy, softheaded, knowledge, crackbrained, spook, balmy, moonstruck, fool, ludicrous, unsound.
I believe you're goin' loony. - "Cy Whittaker's Place", Joseph C. Lincoln.
good looks, screw-loose, break loose, let loose, loose off, loose woman, loose-fitting, loose-jointed, loose-jowled, on the loose.