Synonyms for Annihilate:

n.

mutilate, eat away, vandalize, ravage, trash. liquidate, rub out, blot out, make, beat, help, root, overcome, defeat, knock out, clear. massacre, butcher, slaughter. overwhelm, shellac, drub, overpower, clobber, cream, trounce, thrash, vanquish, steamroller, wallop, smear, win, crush. invalidate, continue, void, negate, vitiate. annihilate (noun)
carry off, extinguish, eradicate, eliminate, wipe out, decimate.

v.

change (verb)
carry off, extinguish, eradicate, eliminate, wipe out, decimate.
destroy (verb)
disintegrate, decimate, smash, exterminate, atomize, destroy, desolate, extirpate, lay waste, eradicate, devastate, level, rip to shreds, tear down, pulverize, flatten, demolish, raze, bulldoze, abolish, wreck, mow down, dismantle, vaporize.
obliterate (verb)
delete, obliterate, cut, erase, expurgate, eliminate, expunge, cancel, edit, omit, annul, strike, censor.
unsubstantiate (verb)
empty, disappear, nullify, vacate.

Other synonyms:

shellac. invalidate, clobber, trounce, overpower, steamroller. cream, vanquish, negate, drub, wallop, crush. liquidate, smear. overwhelm, vitiate. thrash. annul
blot out.
consume
lay waste.
defeat
mow down.
destroy
obliterate, decimate, pulverize.
kill
exterminate.
pillage
ravage.
take apart
dismantle.
Other relevant words:
massacre, mutilate, clobber, steamroller, shellac, drub, butcher, carry off, crush, thrash, rub out, root, overwhelm, extinguish, wallop, trounce, overpower, slaughter, smear, trash, vitiate, negate, blot out, invalidate, vandalize, cream, vanquish, wipe out, void, clear, overcome, liquidate, defeat, ravage, beat.

Usage examples for annihilate

  1. His weary Guards and he seek to annihilate space. – The Life of Napoleon I (Volumes, 1 and 2) by John Holland Rose
  2. Baudin, after his remarkable exploits in 1800 to 1804, was the last man whom Napoleon would have chosen to try to annihilate a British settlement anywhere. – Terre Napoleon A history of French explorations and projects in Australia by Ernest Scott
  3. Speak up, sir, and tell me what you are before I annihilate you again." – The Book of Gud by Dan Spain Harold Hersey